Japanese scientists have developed an efficient method of successfully generating hair growth in nude mice using "bead-based hair follicle germ" (bbHFG). The new method can be scaled up and therefore shows great potential for clinical applications in human hair regenerative therapy.

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Several factors contribute to human hair loss: It can be hereditary, or it can occur as a result of aging, hormonal imbalances or treatment with cancer fighting medications, all of which can lead to the loss of stem cells responsible for hair formation during development and the replacement of hairs that are shed during normal hair cycling.

Hair loss is currently treated with drugs and hair transplantation - where hair follicles are removed from one part of the body to the site of hair loss.

These treatment methods have their limitations; drugs are inefficient at stimulating hair regrowth to the extent necessary to counteract hair loss and hair transplantation doesn't increase hair numbers in the scalp.

To make the method scalable and therefore clinically viable, a team of scientists led by Dr. Tatsuto Kageyama and Prof. Junji Fukuda from Yokohama National University in Japan proposed a new approach to regenerate hair using mouse and human hair follicle stem cells.

The team fabricated hair beads in u-shaped wells in a plate array using hair follicle stem cells encapsulated in collagen, a structural protein in skin believed to play an important role in hair follicle generation during embryonic development and hair regrowth throughout life.

"In this study, we worked on how to prepare tissue grafts. However, to deliver this approach to hair loss patients, we need a proper approach to obtain a sufficient number of hair follicle stem cells before preparing tissue grafts."

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Summary Source | FAQ | Feedback | Top keywords: hair^#1 cell^#2 follicle^#3 method^#4 stem^#5

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This is the best tl;dr I could make, original reduced by 71%. (I'm a bot)Several factors contribute to human hair loss: It can be hereditary, or it can occur as a result of aging, hormonal imbalances or treatment with cancer fighting medications, all of which can lead to the loss of stem cells responsible for hair formation during development and the replacement of hairs that are shed during normal hair cycling.Hair loss is currently treated with drugs and hair transplantation - where hair follicles are removed from one part of the body to the site of hair loss.These treatment methods have their limitations; drugs are inefficient at stimulating hair regrowth to the extent necessary to counteract hair loss and hair transplantation doesn't increase hair numbers in the scalp.To make the method scalable and therefore clinically viable, a team of scientists led by Dr. Tatsuto Kageyama and Prof. Junji Fukuda from Yokohama National University in Japan proposed a new approach to regenerate hair using mouse and human hair follicle stem cells.The team fabricated hair beads in u-shaped wells in a plate array using hair follicle stem cells encapsulated in collagen, a structural protein in skin believed to play an important role in hair follicle generation during embryonic development and hair regrowth throughout life."In this study, we worked on how to prepare tissue grafts. However, to deliver this approach to hair loss patients, we need a proper approach to obtain a sufficient number of hair follicle stem cells before preparing tissue grafts."Summary Source | FAQ | Feedback | Top keywords: hair#1 cell#2 follicle#3 method#4 stem#5Post found in /r/science, /r/Futurology and /r/Health.NOTICE: This thread is for discussing the submission topic. Please do not discuss the concept of the autotldr bot here. https://ift.tt/eA8V8J https://ift.tt/2OwLimF